The concentration of unchanged clofentezine in plasma reached a maximum of 0. Eightynine hours after dosing, 22 29% of the administered 14 c clofentezine in the lowdose groups had been recovered in the urine. A simplified procedure for determination of clofentezine. Two clofentezine products are currently registered in canada under the authority of the pest control products act, including one technical grade active ingredient and one commercial class enduse product. Roe insect diagnostician plant pest diagnostic lab utah state university may 2005. As a result, clofentezine has been classified as a possible human carcinogen based on male rat thyroid follicular cell adenoma andor carcinoma combined tumor rates. Who inventory of evaluations performed by the joint. In accordance with article 12a of the regulation the european food safety authority efsa. Meclofenamate is also used to relieve symptoms of osteoarthritis or rheumatoid arthritis in adults, and juvenile arthritis in children who are at least 14 years old. Soilenvironment in soil, the major degradation route leads to 2chlorobenzoic acid, and finally to co2.
This regulation establishes tolerances for residues of clofentezine in or on grapes and persimmons. Clofentezine, a growth inhibitor, has sublethal effects on lifetable parameters of tetranychus urticae koch females. Compliance with the tolerance levels specified in this paragraph is to be determined by measuring only clofentezine, 3,6bis2chlorophenyl1,2,4,5tetrazine, in or on the commodity. Fao specifications and evaluations for clofentezine page 3 of 24 clofentezine information iso common names clofentezine ansi, bsi, eiso, fiso synonyms none chemical names iupac 3,6bis2chlorophenyl1,2,4,5tetrazine. In order to accommodate for the intended uses of clofentezine, the united kingdom proposed to raise the existing mrl in cucurbits with edible peel to 0. Pdf to jpg online converter convert pdfs to jpg images for free. For a better browsing experience, we recommend that you use a different browser or upgrade to. Free online service to convert a pdf file to a set of optimized jpg images.
The abbreviation cipac stands for collaborative international pesticides analytical council. Program and regulatory information about this substance, including links to epa applicationssystems, statuesregulations, or other sources that track or regulate this substance. Based on the first and scigrow models, the eecs of clofentezine for acute exposures are estimated to be 4. Upload pdf files and we will convert them to high quality. Meclofenamate, as other nsaids may reduce the effects of blood pressurelowering medications.
Pdf clofentezine and hexythiazox resistance in tetranychus. After extraction, residue is cleaned by acetonitrilehexane partition followed by elution through a seppak silica cartridge. Spidermites eggs and adults including the twospotted spider mite, european red mite, mcdaniel spider mite. The clofentezine, with the cas registry number 74115245, is also known as bisclofentezine. Who inventory of evaluations performed by the joint meeting. Dont download software use zamzar to convert it for free online. Free, easy to use online pdf to jpg jpeg converter tool. It offers mass conversion and allows files up to 50 mb. For more information about the substance, you may click one of the links below to take you to the relevant section. The hazard classification and labelling section shows the hazards of a substance based on the standardised system of statements and pictograms established under the clp classification labelling and packaging regulation. Modification of the existing mrls for clofentezine in several.
Rats groups of 5 male and 5 female rats received single oral doses of 0. If you accept without changing your settings, we assume that you are happy to receive all cookies on the lgc website. Final determination by normal phase highperformance liquid chromatography hplc with uv absorption detection. Identification product identifier clofentezine other means of identification product code n11490 recommended use for laboratory use only recommended restrictions none known. This specification, which is part one of this publication, is based on an evaluation of data. Fao specifications and evaluations for clofentezine page 7 of 24.
Pretreatment with clofentezine 10 mgkg diet for 14 days prior to an oral dose of 10 mgkg 14 cclofentezinekg diet did not change the excretion profile nor the residues disposition. We are an international, nonprofitoriented and nongovernmental organization see contact devoted to promote the international agreement on methods for the analysis of pesticides and physicochemical test methods for formulations and to promote interiaboratory programmes for the evaluation of test. Apollo 50 sc contains clofentezine for the use on apples, pears, plums and cherries. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Clofentezine 50%sc, insecticide china pesticide manufacturer. Environmental fate ecotoxicology human health a to z index home. Ae c593600, a transformation product of clofentezine, were studied in a loam soil ph 6.
A selective ovicidal tetrazine acaricide for use in a range of crops including fruit and ornamentals example pests controlled. Convert pdf portable document format to jpg joint photographic experts group jfif format in high quality using this free online file converter. The dt50s of extractable clofentezine residues from both sediment and water in these samples were clofentezine is an ovicidal acaricide. Indicates high toxicity in the given toxicological category. Buy clofentezine cas 74115245, used as a pesticide, from santa cruz biotechnology. It does not include the maximum residue levels mrls that have been recommended by jmpr. Studies conducted in the laboratory with freshly collected sedimentwater samples indicated that clofentezine will partition readily into sediments and will be readily transformed. It belongs to the product categories of agrochemicals. Plants in metabolism studies, unchanged clofentezine was the major extractable residue. Clofentezine is an active substance of plant protection product used as pesticide, acaricide. We have noticed that you are using an old internet browser. This inventory summarizes evaluations of pesticides that have been performed by the joint faowho meeting on pesticide residues jmpr.
Clofentezine and hexythiazox resistance in tetranychus. The clp regulation makes sure that the hazards presented by chemicals are clearly communicated to. Pdf to jpg convert your pdf to jpg for free online zamzar. A selective ovicidal tetrazine acaricide for use in a range of crops including fruit and ornamentals. Index for clofentezine pc code 125501 pesticides us epa.
It is important, therefore, to reduce the dosage of warfarin. Data sources include ibm watson micromedex updated 28 feb 2020, cerner multum updated 2 mar 2020, wolters kluwer updated. Following oral administration, excretion occurs within 2448 hours in the urine and faeces. Convert each pdf page into a jpg or extract all images contained in a pdf. Text searchable document data evaluation record on the adsorptiondesorption of ae c593600, a transformation product of clofentezine, in soil pmra submission number. Trace amounts 4% of 2chlorobenzonitrile, the major photodegradation product, were also detected. Note 3 chemical assay is the only fully reliable method to measure the mass of active ingredient still in suspension. Interregional research project number 4 ir4 requested these tolerances under the federal food, drug, and cosmetic act ffdca. For additional information on toxicity from scientific journals or registration documents, see the additional resources for toxicity section of the chemical detail page. Meclofenamate is used to treat fever or mild to moderate pain in adults. Ovation sc contains one pound of clofentezine per quart of product and is applied to the foliage to control mite infestation. It is an organochlorine acaricide, a member of monochlorobenzenes and a tetrazine. Pdf to jpg convert your pdfs to images online for free. Convert pdf to jpg free pdf to jpg converter, nothing to download, no registration, no watermark.
It is used in agriculture for the protection of ornamentals, food and nonfood crops in the field. It has a role as a mite growth regulator and a tetrazine acaricide. Also low acute toxicity in rats exposed dermally ld50 2100 mgkg. Commons is a freely licensed media file repository. Meclofenamate works by reducing hormones that cause inflammation and pain in the body. Clofentezine is separated from other components by high performance liquid chromatography on a reversed phase column and quantified using benzyl butyl phthalate as internal standard. No mrl was proposed for cherries as the data were insufficient. Epa has sufficient data to assess the hazards of clofentezine 3,6bischlorophenyl1,2,4,5tetrazine and to make a determination on aggregate exposure, consistent with section 408b2, for a tolerance for residues of clofentezine on apples at 0. Concurrent use of meclofenamate and warfarin, a blood thinner, may cause excessive bleeding as meclofenamate enhances the effect of warfarin. Buy high purity clofentezine analytical standards from chem service inc. After a reevaluation of clofentezine, health canadas pest management regulatory agency pmra, under the authority of the pest control products act, is granting continued registration of products containing clofentezine for sale and use in canada. Clofentezine and hexythiazox resistance in tetranychus urticae koch in australia article pdf available in experimental and applied acarology 176. The q 1 value for use in clofentezine risk assessment using the 34 inter species scaling factor is 3.
A suspension concentrate contact and residual acaricide, controlling eggs and young larvae of the mites in crops as indicated. Clofentezine residues were shown to be stable over 2 years in high water containing matrices. Oct 07, 2014 in accordance with article 6 of regulation ec no 3962005, the united kingdom, hereafter referred to as the evaluating member state ems, received an application from makteshimagan uk ltd to modify the existing mrls for the active substance clofentezine in several commodities. Pdf to jpg online converter convert pdf to jpg for free. Clofentezine is a tetrazine that is 1,2,4,5tetrazine in which both of the hydrogens have been replaced by ochlorophenyl groups. For a better browsing experience, we recommend that you use a different browser or upgrade to a newer version of your browser. This chemicals molecular formula is c 14 h 8 cl 2 n 4 and molecular weight is. Clofentezine analytical standards 74115245, n11490100mg. Apollo 50 sc gives excellent control of red spider mite and some control of apple rust mite.
Easily convert pdf to jpg with this free online converter. Clofentezine is highly toxic to some aquatic organisms but has very low solubility, degrades rapidly, and has very low soil mobility once applied. Clofentezine, an acaricide, was first evaluated by the jmpr in 1986 and reevaluated for residues several times up to 1992. Clofentezine was included in annex i to directive 91414eec on 1 july 2008 pursuant to article 11b of the regulation ec no 14902002 hereinafter referred to as the regulation. Clofentezine, 3,6bis 2chlorophenyl1,2,4,5tetrazine, is a specific acaricide with contact action, and long residual activity, figure 1. Clofentezine is considered to be a mild eye irritant toxicity category iv and practically nonirritating to the skin toxicity category iv, but is considered to be a weak skin sensitizer based on a guinea pig maximization assay. Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Since dwlocs address total aggregate exposure to clofentezine, they are further discussed in the aggregate risk sections in unit iii.
Toxicity to humans as with other mammals, clofentezine does not pose a high toxicity risk to humans. Information from its description page there is shown below. All image quality and resolution will remain intact. Reevaluation decision rvd201404, clofentezine canada. For additional information on toxicity from scientific journals or registration documents, see the additional resources for toxicity section of the chemical detail page 1. Indicates no available weightoftheevidence summary assessment. The dt50s of extractable clofentezine residues from both sediment and water in these samples were clofentezine in or on multiple commodities which are identified and discussed later in this document. Purchase online clofentezine drec11680000 cas number 74115245. Use the pdf to jpeg converter to transform entire pdf pages into highquality jpg images. Meclofenamate sodium pill images what does meclofenamate.431 1261 967 340 248 228 1096 188 331 90 554 233 611 892 571 635 1309 726 1621 553 1099 27 1420 1279 867 669 180 926 898 602 262 361 1047 516 411 1004 83 239 1412 531 537 350 696 1390 1332 1465 714 657